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Cell and gene therapy logistics

Advanced therapy transport solutions

Our full-service logistics and storage solutions help you seamlessly deliver innovation

Cell and gene therapy (CGT) logistics must overcome critical challenges that historically have affected the global cell therapy supply chain. Complex cell therapy logistics require precise temperature control and time-sensitive delivery. Explore how World Courier's cutting-edge solutions streamline these processes to ensure the safe and efficient transport of these groundbreaking therapies. Discover how we are revolutionizing the CGT supply chain as an advanced therapy logistics provider. Learn more about our comprehensive services and global expertise:

  • An introduction to CGT
  • CGT logistics solutions
  • CGT supply chain challenges
  • The World Courier difference 

What is cell and gene therapy – and how does the supply chain work?

Cell and gene therapies (CGTs) represent the leading edge of biomedical research. Autologous and allogeneic cell, gene, and tissue therapies are transforming healthcare. Approvals of autologous CAR-T therapies such as Kymriah, Tecartus, and Yescarta and allogeneic treatments including Rethymic and Alofisel reinforce the advancements in this space.

CGT sponsors must consider every aspect of their development and manufacturing journey as early as possible to ensure their discovery therapy can be approved and commercialized without delay. 

Planning for all stages of cell therapy logistics — including development, clinical trials, and commercialization — is a crucial part of this process. However, CGTs come with unique logistic requirements that add complexity and risk to their supply chains. Understanding the end-to-end supply chain of CGTs early ensures risks are mitigated before they cause delays in getting treatment to patients. Key aspects of a robust cold supply chain:

  • Global real-time temperature and location monitoring
  • 24/7 support
  • Compliance support for import/export requirements special handling requirements
  • Cryogenic packaging, storage, and transportation

Providing cell and gene therapy logistics solutions

World Courier is a trusted partner in the cell and gene therapy supply chain, offering specialized solutions tailored to your needs. We have over five decades of experience in specialist logistics and have been transporting CGTs since 2005. We excel in cell therapy logistics, ensuring secure and timely transportation of stem cells and advanced therapies. Our dedicated team, backed by cutting-edge technologies, oversees the entire cell therapy supply chain. We pride ourselves on our seamless, efficient, and compliant cell therapy logistics services.

Supporting advanced therapy solutions

As a dedicated cell therapy logistics provider, we have been supporting advanced therapies since 2005. Our commitment to quality is evident through the delivery of over 32,000 shipments to more than 2,000 clinical sites in 2022. Our comprehensive cell therapy logistics solutions and robust supply chain management ensure that these life-saving treatments reach patients safely and efficiently. 
A gloved hand uses forceps to place a vial of liquid into a thermal container surrounded by fog.

Temperature-controlled solutions 

Safe and secure shipments with qualified packaging, supporting temperature ranges of +15°C to +25°C for fresh cells and -190°C for frozen. We also hold a global network of 18 liquid nitrogen (LN2) charging centers, in addition to more than 120 charging stations. We provide  a temperature-controlled cell and gene therapy supply chain for your products.
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Quality systems

World Courier stands at the forefront of advanced therapy supply chain logistics as the first logistics company to attain global certification against three major GDP standards in 2017. Our commitment to quality ensures that every shipment follows a dedicated standard operating procedure (SOP) across our extensive network. As a leading cell therapy logistics provider, our rigorous standards set us apart, assuring safe and efficient delivery of your products.

Rising to the cell and gene therapy supply chain challenge

World Courier excels in transporting cell and gene therapies. With hubs located worldwide, we ensure reliable delivery, temperature monitoring, and specialized packaging maintain therapy integrity. Tailored logistics plans address unique therapy needs. Expertise in regulatory frameworks speeds up customs clearance.
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Global cryogenic charging locations

To support the growth of the advanced therapy solutions industry and enable more patients than ever before to be treated with these life-changing therapies, World Courier can charge across its network of more than 120+ offices globally.

Through this global network, we help advanced therapy companies build robust logistics platforms that support the clinical development and commercialization of therapies to meet patient treatment needs.

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Solutions that grow with your needs

We’re here to guide you through the complexities of cell therapy logistics management. From the initial stages of a clinical trial to the development of your platform for commercial success, we offer scalable solutions. Our proficiency in managing the cell therapy supply chain has made us a trusted partner in this sector. Explore how our technology ensures the safe transit of your shipments.
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World Courier difference

Managing biopharmaceutical complexities with care, our highly trained and specialized teams have been developed to ensure the safety of your shipments, no matter what the unique challenge may be. From clinical to commercial, your product is protected at every step.  Discover a cell therapy logistics solution that supports your organization and delivers your product to patients around the world.        
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Working with our partners

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Collaboration is essential to the creation of clinical and commercial scale cell therapy logistics solutions. In order to support therapy developers, we have integrated systems and technology with a number of key partner organizations. We have established ourselves as a trusted partner within the cell therapy supply chain. Our goal remains the same, to ensure safe and efficient delivery of life-changing cryogenic transport for gene therapy products to patients who need them most.
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Why choose World Courier?

World Courier has specialist expertise in cell and gene therapy logistics. We are proud of our ability to collaborate with diverse organizations across the globe. These key attributes ensure the safe transport of critical medical supplies to those who need them most.

We recognize that in pharmaceutical logistics there is no room for error. Each shipment is handled with the utmost care. Our meticulous planning ensures that shipments arrive at their destination in optimal condition. Safeguarding patient health is our commitment. 

Our team is made up of individuals with a high-level understanding of the pharma and healthcare industries. Their expertise enables them to offer innovative solutions so pharmaceutical integrity is preserved. With cold chain packaging materials to support shipments, we have got you covered.


Global LN2 charging capability

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company-owned facilities globally

Our pharmaceutical delivery credentials

World Courier is a trusted provider of cell therapy supply chain management and pharmaceutical delivery services.

We prioritize quality and go beyond compliance to optimize the cell therapy supply chain. Our teams ensure regulatory compliance and mitigate risks through training and communication. By engaging stakeholders on a shipment-by-shipment basis, we deliver quality that exceeds minimum requirements. Trust us for secure and compliancy throughout your commercialization journey.

Other international guidelines we adhere to:

  • GDP compliant
  • National and State Board of Pharmacy licensed (where applicable)
  • WHO good Distribution practices for pharmaceutical products, TRS No. 957 Annex 5
  • EU Guidelines on good distribution practice of medicinal products for human use (2013/C 343/01)
  • USP <1079> Good Storage and Shipping Practices for Drug Products, US Pharmacopeia
  • Code of Federal Regulations (CFR) 21 Part 11 compliant
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Cell and gene therapy success stories

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Read the latest cell and gene therapy-specific articles, white papers, and peer-reviewed papers from World Courier and a range of logistics leaders. 
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Cold hard facts about cryogenic cell and gene therapy logistics

World Courier
October 2022

Cell and Gene Therapy Cryo


White paper: Cell and gene therapy trials — The synergy of CRO and specialty logistics collaboration

Andrea Zobel
World Courier
October 2023

Cell and gene therapy FAQs

Are CGTs dangerous goods?

Cell and gene therapies are not inherently dangerous goods. However, the materials used in their production and transportation, such as viral vectors or cryopreserved cells, may have components that are classified as hazardous. Proper handling and adherence to regulations are crucial to ensure the safety of individuals in their transport and administration.

How do you ensure CGTs stay within the right temperature range?

To maintain the precise temperature range required for cell and gene therapies we use a range of cutting-edge technology. We use specially designed temperature-controlled packaging to safeguard these sensitive products during transport. Our dedicated team monitors and maintains the temperature throughout the logistics chain. This ensures therapies remain within the appropriate temperature range. Protecting the efficacy of cell therapy distribution for patients worldwide is our priority.

How have cell and gene therapies evolved?

CGTs have  evolved by harnessing genetic engineering and cellular manipulation to treat a wide range of diseases. Initially experimental, it has progressed to clinical success with FDA-approved therapies. An example is the development of CAR-T cell treatments for cancer. Advances in gene editing tools like CRISPR have expanded its potential. CGTs have shifted from theoretical promise to real-world medical solutions. This offers hope for previously untreatable conditions, including genetic disorders and various cancers. As a cell therapy logistics provider, we are excited to drive the future of CGTs.

Why are CGTs so crucial today? 

Cell and gene therapies are crucial because they offer a cutting edge approach to treating  diseases. They offer personalized treatments for conditions like cancer and genetic disorders, holding the potential to revolutionize healthcare. With fewer side effects and the ability to address the causes of illnesses, these therapies offer new hope for patients who had limited options in the past, providing a path towards better outcomes and improved quality of life.

Why is temperature-controlled transportation so important?

Temperature-controlled transport of cell and gene therapies is crucial. This is because these therapies are sensitive to temperature changes. Any temperature deviation could lead to damage to cells or genetic material. Maintaining precise temperature conditions is essential for advanced therapy logistics. Reliable temperature control ensures treatments are safe for patient use. 

Revolutionize your advanced therapy supply chain with us

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